Fluoxetine brakes the menstrual cycle: Uncovering the unexpected effect

Fluoxetine brakes the menstrual cycle: Uncovering the unexpected effect

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Fluoxetine is one of the most commonly used antidepressants, classified under selective serotonin reuptake inhibitors (SSRIs).It is indicated for the treatment of depression, obsessive-compulsive disorder, anxiety, and eating disorders.The antidepressant effect of fluoxetine is achieved by inhibiting the reuptake of serotonin (5-HT) via the serotonin transporter (SERT) in neurons.

Although fluoxetine is generally considered safe and well-tolerated by most patients, this case series describes Matching Shirts instances where patients Queen/Full Panel Headboard treated with fluoxetine subsequently developed menstrual irregularities.Upon discontinuation of fluoxetine, the menstrual cycles returned to normal.To the best of our knowledge, there is a lack of precise data associating fluoxetine with the onset of menstrual irregularities.

This effect may be related to its central serotonergic action via 5-HT action modulates the prolactin, estradiol, and progesterone level.Therefore, physicians should be aware of the potential risk of fluoxetine-induced menstrual irregularities.